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Symbol Name ID |
Usp14
ubiquitin specific peptidase 14 MGI:1928898 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | nervous system phenotype |
increased neuron apoptosis |
abnormal brain morphology |
decreased midbrain size |
abnormal brain commissure morphology |
decreased corpus callosum size |
decreased hippocampal commissure size |
abnormal cingulum morphology |
abnormal brainstem morphology |
abnormal pons morphology |
abnormal pontine nuclei morphology |
abnormal limbic system morphology |
abnormal dentate gyrus morphology |
abnormal hippocampus pyramidal cell morphology |
small hippocampus |
abnormal hindbrain morphology |
Purkinje cell degeneration |
abnormal cerebellar granule cell morphology |
small cerebellum |
abnormal neuromuscular synapse morphology |
abnormal spinal nerve morphology |
abnormal spinal cord morphology |
abnormal spinal cord white matter morphology |
axonal dystrophy |
abnormal nervous system physiology |
impaired synaptic plasticity |
abnormal synaptic transmission |
reduced long-term potentiation |
decreased post-tetanic potentiation |
increased synaptic depression |
abnormal miniature endplate potential |
abnormal neurotransmitter secretion |
decreased paired-pulse facilitation |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
| Usp14ax-J/Usp14ax-J | ||||||||||||||||||||||||||||||||||
| Usp14nmf375/Usp14nmf375 | * | |||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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